Bioinformatics & Cheminformatics

Novel Drug Discovery

We are carrying out the projects on Cancer, HIV/AIDS, Diabetes, Hepatitis, Influenza, Schizophrenia, Malaria, Parkinson's disease, Alzheimer's disease, Cardiovascular, Measles, Tuberculosis by initiating from the Gene sequence of the patient and finally evolving with a suitable drug for curing that disease. Project comprises of Computational Genome Sequence Analysis, Phylogenetic Analysis, Protein Sequence Analysis, Homology Modeling, Protein structure prediction, Molecular Modeling, Computer Aided Drug designing, Virtual screening and Docking.

Clinical Research, Pharma Research, Pharmacovigilance & Clinical Data Management - CDM

• MBBS, MD,BDS, BHMS, BUMS, BAMS, BPT
• M.Sc., (Microbiology   / Biochemistry   / Biotechnology  / Bio-informatics / Chemistry / Genetics / Botany  / Zoology  / Life Sciences / Biomedical Genetics / Molecular Biosciences / Statistics / Nursing)
• B.Pharmacy, M.Pharmacy, B.Tech.(Biotechnology)

Clinical Research

The most commonly performed clinical trials evaluate new drugs, medical devices, biologics, or other interventions to patients in strictly scientifically controlled settings, and are required for regulatory authority (in the USA, the Food and Drug Administration) approval of new therapies. Trials may be designed to assess the safety and efficacy of an experimental therapy, to assess whether the new intervention is better than standard therapy, or to compare the efficacy of two standard or marketed interventions. The trial objectives and design are usually documented in a Clinical trial protocol.

Pharmacovigilance

Pharmacovigilance is a discipline which is concerned with identifying, validating, quantifying, evaluating and minimizing the adverse effects of medicine thereby increasing the safety of drugs in use. It is a study of drug related adverse effect carried out by pharmaceutical industries to suggest warnings and recommendation for product withdrawal.

Pharmacovigilance plays an important role in the use of medicines by providing information about ADRs in the general population. Knowledge of the adverse effects of drugs is important for effective treatment. Communicating the potential harm of drug-use to patients is a matter of high priority and should be carried out by every prescriber. Information collected during the pre-marketing phase of drug development may not detect rare ADRs. The use of a drug during a clinical trial is under controlled conditions. Clinical trials generally enroll a selected, limited number of patients and may not include certain sections of the population. Drug use in special situations or drug interactions may not be studied. Therefore, the post-marketing surveillance of drugs is important. The use of traditional and complementary drugs (e.g. herbal remedies) may also pose specific toxicological problems, when used alone or in combination with other drugs. Therefore, Pharmacovigilance is needed for detecting ADRs and specifically to combat counterfeit and substandard quality products. ADR monitoring ensures that patients obtain safe and efficacious products. Pharmacovigilance plays an important role in ensuring drug safety.

Pharamcovigilance improves patient care and safety in relation to the use of medicines and all medical and paramedical interventions. It also contributes to the assessment of benefit, harm, effectiveness and risk of medicines, encouraging safety and more effective use.

CDM - Clinical Data Management

You will be extensively involved in:

SAS, Biostatistics & Project in Clinical Research

• MBBS, MD,BDS, BHMS, BUMS, BAMS, BPT
• M.Sc., (Microbiology / Biochemistry / Biotechnology / Bioinformatics / Chemistry / Genetics / Botany / Zoology / Life Sciences / Biomedical Genetics / Molecular Biosciences /Statistics / Nursing)
  
• B.Pharmacy, M.Pharmacy, B.Tech.(Biotechnology)

Statistical analysis plays a predominant role in finding the safety and efficacy of a drug in Clinical Research. It has assumed tremendous importance with the advanced research in life sciences. It deals with the theories and methods of collection, analysis and interpretation of data. It plays a major role in Clinical Research because data of Clinical Research are of a variable nature. It is very difficult to draw a concrete conclusion from Clinical Research because of inherent differences between two individuals and also from group to group. The extent of this variability in a character is by way of chance, i.e., biological or normal is revealed by statistical methods. Interpretation, drawing conclusions and recommendations play a major role in Clinical Research.

You will be extensively involved in: